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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Immunofluorescence analysis of Hela cells using PTGS2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of Hela cells using PTGS2 mouse mAb (green) and negative control (red).
Flow cytometric analysis of HepG2 cells using PTGS2 mouse mAb (green) and negative control (red).
Flow cytometric analysis of HT-29 cells using PTGS2 mouse mAb (green) and negative control (red).
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Mouse Monoclonal Antibody to PTGS2

  • 货号:

    32175
  • 别名:

    COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P35354
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PTGS2

Description

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

References

1,PLoS One. 2020 Sep 30;15(9):e0239856.
2,Acta Gastroenterol Belg. Apr-Jun 2020;83(2):249-254.

Specification

Aliases COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS
Entrez GeneID 5743
Swissprot P35354
clone 4C1H7
WB Predicted band size 69kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PTGS2 (AA: 18-207) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000