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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using DSG3 mouse mAb against A431 cell lysate.
Flow cytometric analysis of A431 cells using DSG3 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using DSG3 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human esophageal tissues using DSG3 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to DSG3

  • 货号:

    30627
  • 别名:

    PVA; CDHF6
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P32926
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Mouse Monoclonal Antibody to DSG3

Description

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

References

1. J Dermatol Sci. 2012 Feb;65(2):102-9.
2. Am J Pathol. 2009 May;174(5):1629-37.

Specification

Aliases PVA; CDHF6
Entrez GeneID 1830
Swissprot P32926
clone 6G2C11
WB Predicted band size 107.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human DSG3 (AA: 55-159) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000