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EIF3C Antibody (Center) (Cat. #P31622) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the EIF3C antibody detected the EIF3C protein (arrow).

Rabbit Polyclonal Antibody to EIF3C

货号：
P31622
别名：
Eukaryotic translation initiation factor 3 subunit C {ECO:0000255|HAMAP-Rule:MF_03002}, eIF3c {ECO:0000255|HAMAP-Rule:MF_03002}, Eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255|HAMAP-Rule:MF_03002}, eIF3 p110 {ECO:0000255|HAMAP-Rule:MF_03002}, EIF3C {ECO:0000255|HAMAP-Rule:MF_03002}
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q99613
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to EIF3C

Description
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Description

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

Specification
Aliases	Eukaryotic translation initiation factor 3 subunit C {ECO:0000255\|HAMAP-Rule:MF_03002}, eIF3c {ECO:0000255\|HAMAP-Rule:MF_03002}, Eukaryotic translation initiation factor 3 subunit 8 {ECO:0000255\|HAMAP-Rule:MF_03002}, eIF3 p110 {ECO:0000255\|HAMAP-Rule:MF_03002}, EIF3C {ECO:0000255\|HAMAP-Rule:MF_03002}
Entrez GeneID	8663
Swissprot	Q99613
WB Predicted band size	105.3kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This EIF3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 538-566 amino acids from the Central region of human EIF3C.
Formulation	Purified antibody in PBS with 0.05% sodium azide.