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Mouse Monoclonal Antibody to SDC1
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to SDC1
Western blot analysis using SDC1 mouse mAb against MCF-7 (1), Hela (2), HepG2 (3), T47D (4), SW620 (5), Jurkat (6) and NIH/3T3 (7) cell lysate.
Mouse Monoclonal Antibody to SDC1
Immunofluorescence analysis of HepG2 cells using SDC1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Mouse Monoclonal Antibody to SDC1
Flow cytometric analysis of HepG2 cells using SDC1 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to SDC1
Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using SDC1 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to SDC1
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using SDC1 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to SDC1
Mouse Monoclonal Antibody to SDC1
Mouse Monoclonal Antibody to SDC1
Mouse Monoclonal Antibody to SDC1
Mouse Monoclonal Antibody to SDC1
Mouse Monoclonal Antibody to SDC1

Mouse Monoclonal Antibody to SDC1

  • 货号:

    30602
  • 别名:

    SDC; CD138; SYND1; syndecan
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF,FCM
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P18827
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to SDC1

Description

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.




References

1. Am J Clin Pathol. 2012 Mar;137(3):423-8.
2. PLoS One. 2011;6(9):e25252.

Specification

Aliases SDC; CD138; SYND1; syndecan
Entrez GeneID 6382
Swissprot P18827
clone 1A3H4
WB Predicted band size 32.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human SDC1 (AA: 28-171) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
IF/ICC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000