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Mouse Monoclonal Antibody to GABBR2
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to GABBR2
Immunofluorescence analysis of Hela cells using GABBR2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Mouse Monoclonal Antibody to GABBR2
Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using GABBR2 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to GABBR2
Mouse Monoclonal Antibody to GABBR2
Mouse Monoclonal Antibody to GABBR2

Mouse Monoclonal Antibody to GABBR2

  • 货号:

    30603
  • 别名:

    HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O75899
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to GABBR2

Description

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.



References

1. J Biol Chem. 2007 Feb 9;282(6):4162-71.
2. Genomics. 1999 Mar 15;56(3):288-95.

Specification

Aliases HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
Entrez GeneID 9568
Swissprot O75899
clone 5G7F7
WB Predicted band size 105.8kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/200 - 1/1000
IF/ICC 1/200 - 1/1000
ELISA 1/10000