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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunofluorescence analysis of Hela cells using GABBR2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Immunohistochemical analysis of paraffin-embedded human cerebellum tissues using GABBR2 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to GABBR2

  • 货号:

    30603
  • 别名:

    HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O75899
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to GABBR2

Description

The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.



References

1. J Biol Chem. 2007 Feb 9;282(6):4162-71.
2. Genomics. 1999 Mar 15;56(3):288-95.

Specification

Aliases HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
Entrez GeneID 9568
Swissprot O75899
clone 5G7F7
WB Predicted band size 105.8kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human GABBR2 (AA: 319-483) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/200 - 1/1000
IF 1/200 - 1/1000
ELISA 1/10000