提醒成功

搜索
Rabbit Polyclonal Antibody to CDH10 (N-term)
-
货号:
P30221 -
别名:
Cadherin-10, T2-cadherin, CDH10 -
应用:
WB,IHC,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q9Y6N8 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980

Rabbit Polyclonal Antibody to CDH10 (N-term)
Description |
---|
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. |
Specification |
|
---|---|
Aliases | Cadherin-10, T2-cadherin, CDH10 |
Entrez GeneID | 1008 |
Swissprot | Q9Y6N8 |
WB Predicted band size | 88.5kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | This CDH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human CDH10. |
Formulation | Purified antibody in PBS with 0.05% sodium azide,1%BSA and 50% glycerol.prepared by Saturated Ammonium Sulfate (SAS) . |
Application |
|
---|---|
WB | 1/1000 |
IHC | 1/100-1/500 |
FCM | 1/10-1/50 |
Product Image
- Western blot analysis of CDH10 Antibody (N-term) in CEM cell line lysates (35ug/lane). CDH10 (arrow) was detected using the purified Pab.
- Flow cytometric analysis of CEM cells using Cadherin 10 (CDH10) Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
- Formalin-fixed and paraffin-embedded human brain tissue reacted with CDH10 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P30221

相关产品


