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Western blot analysis of LEF1 in C6 lysates using LEF1 antibody.
Western blot analysis of LEF1 in Jurkat lysates using LEF1 antibody
Immunocytochemistry analysis of LEF1 (green) in Jurkat using LEF1 antibody,and DAPI(blue).
Immunohistochemistry analysis of paraffin-embedded Human tonsil using LEF1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
HOT

Rabbit Polyclonal Antibody to LEF1

  • 货号:

    P23515
  • 别名:

    LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IHC,IF,FCM
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9UJU2
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to LEF1

Description

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).

Specification

Aliases LEF1; Lymphoid enhancer-binding factor 1; LEF-1; T cell-specific transcription factor 1-alpha; TCF1-alpha
Entrez GeneID 51176
Swissprot Q9UJU2
WB Predicted band size Calculated MW: 44 kDa; Observed MW: 25-58 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen A synthetic peptide of human LEF1
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200
FCM 1/50-1/100