Rabbit Polyclonal Antibody to TDP 43

Description
TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Specification
Aliases	ALS10; TDP-43
Entrez GeneID	23435
Swissprot	Q13148
WB Predicted band size	Calculated MW: 45 kDa; Observed MW: 45 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Zebrafish
Immunogen	A synthesized peptide derived from human TDP43
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500-1/1000
IP	1/10-1/20
IHC	1/50-1/100
IF/ICC	1/50-1/200
FCM	1/50-1/100