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Mouse Monoclonal Antibody to TNFRSF11B
-
货号:
30136 -
别名:
OPG; TR1; OCIF; MGC29565; TNFRSF11B -
应用:
IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O00300 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to TNFRSF11B
Description |
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
References |
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1. Am J Hypertens. 2009 Nov;22(11):1167-70. 2. Am J Hum Genet. 2009 Nov;85(5):628-42. |
Specification |
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Aliases | OPG; TR1; OCIF; MGC29565; TNFRSF11B |
Entrez GeneID | 4982 |
Swissprot | O00300 |
clone | 5A11 |
WB Predicted band size | 60kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human TNFRSF11B expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
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IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30136

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