TNFRSF11B[30136]
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Immunohistochemical analysis of paraffin-embedded human mammary cancer tissues (left) and lung cancer tissues (right) using TNFRSF11B mouse mAb with DAB staining.

Mouse Monoclonal Antibody to TNFRSF11B

  • 货号:

    30136
  • 别名:

    OPG; TR1; OCIF; MGC29565; TNFRSF11B
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O00300
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to TNFRSF11B

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

References

1. Am J Hypertens. 2009 Nov;22(11):1167-70.
2. Am J Hum Genet. 2009 Nov;85(5):628-42.

Specification

Aliases OPG; TR1; OCIF; MGC29565; TNFRSF11B
Entrez GeneID 4982
Swissprot O00300
clone 5A11
WB Predicted band size 60kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IHC 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30136