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Mouse Monoclonal Antibody to CDKN1C

  • 货号:

    30130
  • 别名:

    BWS; WBS; p57; BWCR; KIP2; CDKN1C
  • 产品上架时间:

    2024-01-01
  • 应用:

  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P49918
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CDKN1C

Description

The protein encoded by this gene is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.Tissue specificity: Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.

References

1. Cell Cycle. 2007 Mar 1;6(5):620-5.
2. Oncogene. 2008 Sep 25;27(43):5651-61.

Specification

Aliases BWS; WBS; p57; BWCR; KIP2; CDKN1C
Entrez GeneID 1028
Swissprot P49918
clone 3E3
WB Predicted band size 57kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CDKN1C expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

ELISA 1/10000

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30130