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Mouse Monoclonal Antibody to CD86
-
货号:
30107 -
别名:
B70; B7-2; LAB72; CD28LG2; MGC34413; CD86 -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P42081 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to CD86
Description |
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This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes. |
References |
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1. Clin Exp Allergy. 2009 Dec;39(12):1852-6. 2. Am J Hum Genet. 2009 Nov;85(5):628-42. 3. Immunology. 2009 Nov;128(3):334-41. |
Specification |
|
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Aliases | B70; B7-2; LAB72; CD28LG2; MGC34413; CD86 |
Entrez GeneID | 942 |
Swissprot | P42081 |
clone | 1B3 |
WB Predicted band size | 52kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD86 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30107

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