Mouse Monoclonal Antibody to ERN1

Description
The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

References
1. Biochem Biophys Res Commun. 2004 Apr 30;317(2):390-6. 2. Mol Cell Biol. 2005 Sep;25(17):7522-33. 3. Science. 2007 Nov 9;318(5852):944-9.

Specification
Aliases	IRE1; IRE1P; IRE1a; hIRE1p; FLJ30999; MGC163277; MGC163279; ERN1
Entrez GeneID	2081
Swissprot	O75460
clone	9F2
WB Predicted band size	109kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human ERN1(aa282-433) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500 - 1/2000
IHC	1/200 - 1/1000
ELISA	1/10000