Mouse Monoclonal Antibody to PRDM1

Description
PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

References
1. Nat Cell Biol. 2006 Jun;8(6):623-30. 2. Int J Hematol. 2007 Dec;86(5):429-37. 3. Nat Genet. 2008 Aug;40(8):955-62.

Specification
Aliases	BLIMP1; PRDI-BF1; MGC118922; MGC118923; MGC118924; MGC118925; PRDM1
Entrez GeneID	639
Swissprot	O75626
clone	5E7
WB Predicted band size	88kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Purified recombinant fragment of human PRDM1 expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	1/500 - 1/2000
ELISA	1/10000