Rabbit Monoclonal Antibody to ANO6

Enables gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including bleb assembly; inorganic ion transmembrane transport; and positive regulation of transport. Acts upstream of or within several processes, including bone mineralization involved in bone maturation; calcium activated phospholipid scrambling; and dendritic cell chemotaxis. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and viscerocranium. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6). [provided by Alliance of Genome Resources, Apr 2022]