Rabbit Monoclonal Antibody to SRA1

Both long non~coding and protein~coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non~coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non~NR activities, including metabolism, adipogenesis and chromatin organization. The long non~coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non~coding RNA. [provided by RefSeq, Mar 2012]