Rabbit Monoclonal Antibody to MRP4

The protein encoded by this gene is a member of the superfamily of ATP~binding cassette (ABC) transporters. ABC proteins transport various molecules across extra~ and intra~cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi~drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin~mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]