Rabbit Monoclonal Antibody to S100 alpha

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF~hand calcium~binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+~induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C~mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies. [provided by RefSeq, Jul 2008]