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Rabbit Monoclonal Antibody to ALKBH5
-
货号:
58317 -
别名:
ABH5; OFOXD; OFOXD1 -
应用:
WB,IHC -
反应种属:
Human, Mouse, Rat -
抗体类型:
Primary antibody -
Swissprot:
Q6P6C2 -
规格:
-
数量:
-+ -
说明书:
目录价¥1280
Rabbit Monoclonal Antibody to ALKBH5
Description |
|---|
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6~methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6~methyladenosine in single~stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha~ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity). |
Specification |
|
|---|---|
| Aliases | ABH5; OFOXD; OFOXD1 |
| Swissprot | Q6P6C2 |
| clone | 6A5F7 |
| WB Predicted band size | 44kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | A synthesized peptide derived from it |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/500~1/2000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#58317
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