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Rabbit Monoclonal Antibody to ALKBH5
Western blot analysis of extracts from HeLa cells at 1:1000.
Rabbit Monoclonal Antibody to ALKBH5

Rabbit Monoclonal Antibody to ALKBH5

  • 货号:

    58317
  • 别名:

    ABH5; OFOXD; OFOXD1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q6P6C2
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to ALKBH5

Description

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6~methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6~methyladenosine in single~stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha~ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

Specification

Aliases ABH5; OFOXD; OFOXD1
Swissprot Q6P6C2
clone 6A5F7
WB Predicted band size 44kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen A synthesized peptide derived from it
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/1000
IHC 1/500~1/2000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#58317