Rabbit Monoclonal Antibody to FGL1

Fibrinogen~like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta~ and gamma~ subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet~binding site, cross~linking region and a thrombin~sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]