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Mouse Monoclonal Antibody to Proteinase 3
-
货号：
20373 -
别名：
PRTN3; ACPA; CANCA -
应用：
-
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
P24158 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Mouse Monoclonal Antibody to Proteinase 3
Description |
|---|
Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis. |
References |
|---|
| 1. Blood. 2007 Dec 1;110(12):4086-95. 2. Clin Exp Immunol. 2006 Jul;145(1):63-70. |
Specification |
|
|---|---|
| Aliases | PRTN3; ACPA; CANCA |
| Entrez GeneID | 5657 |
| Swissprot | P24158 |
| clone | 3B4 |
| WB Predicted band size | 28kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human Proteinase 3 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20373
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