Rabbit Monoclonal Antibody to DGCR8

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double~stranded RNA binding protein that functions as the non~catalytic subunit of the microprocessor complex. This protein is required for binding the double~stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]