Rabbit Monoclonal Antibody to TRAPPC2

The protein encoded by this gene is thought to be part of a large multi~subunit complex involved in the targeting and fusion of endoplasmic reticulum~to~Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c~myc promoter~binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]