Rabbit Monoclonal Antibody to COX5B

Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi~subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial~ and nuclear~encoded subunits. The mitochondrially~encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear~encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear~encoded subunit Vb of the human mitochondrial respiratory chain enzyme. [provided by RefSeq, Jul 2008]