Rabbit Monoclonal Antibody to EHD1

This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain~containing proteins. The protein~binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein~protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]