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Western blot detection of TPMT in Hela,A549,HL~60 cell lysates using TPMT antibody(1:1000 diluted).
Rabbit Monoclonal Antibody to TPMT
-
货号：
57692 -
别名：
TPMTD -
应用：
WB,IHC,IF,FCM,IP -
反应种属：
Human, Mouse, Rat -
抗体类型：
Primary antibody -
Swissprot：
P51580 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to TPMT
Description |
|---|
This gene encodes the enzyme that metabolizes thiopurine drugs via S~adenosyl~L~methionine as the S~methyl donor and S~adenosyl~L~homocysteine as a byproduct. Thiopurine drugs such as 6~mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S~methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014] |
Specification |
|
|---|---|
| Aliases | TPMTD |
| Swissprot | P51580 |
| clone | 6B7A6 |
| WB Predicted band size | 28kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | A synthesized peptide derived from it |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000 |
| IP | 1/20 |
| IHC | 1/50 |
| IF/ICC | 1/50 |
| FCM | 1/20~1/100 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#57692
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