Rabbit Monoclonal Antibody to SOX10

This gene encodes a member of the SOX (SRY~related HMG~box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg~Shah and Waardenburg~Hirschsprung disease. [provided by RefSeq, Jul 2008]