Rabbit Monoclonal Antibody to SH3PX1

This gene encodes a member of the sorting nexin family. Members of this family contain a phosphoinositide binding domain, and are involved in intracellular trafficking. The encoded protein does not contain a coiled coil region, like some family members, but does contain a SRC homology domain near its N~terminus. The encoded protein is reported to have a variety of interaction partners, including of adaptor protein 2 , dynamin, tyrosine kinase non~receptor 2, Wiskott~Aldrich syndrome~like, and ARP3 actin~related protein 3. The encoded protein is implicated in several stages of intracellular trafficking, including endocytosis, macropinocytosis, and F~actin nucleation. [provided by RefSeq, Jul 2013]