Rabbit Monoclonal Antibody to Galectin 3

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta~galactosides. The encoded protein is characterized by an N~terminal proline~rich tandem repeat domain and a single C~terminal carbohydrate recognition domain. This protein can self~associate through the N~terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T~cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]