Rabbit Monoclonal Antibody to CD26

The DPP4 gene encodes dipeptidyl peptidase 4, which is identical to adenosine deaminase complexing protein~2, and to the T~cell activation antigen CD26. It is an intrinsic type II transmembrane glycoprotein and a serine exopeptidase that cleaves X~proline dipeptides from the N~terminus of polypeptides. Dipeptidyl peptidase 4 is highly involved in glucose and insulin metabolism, as well as in immune regulation. This protein was shown to be a functional receptor for Middle East respiratory syndrome coronavirus (MERS~CoV), and protein modeling suggests that it may play a similar role with SARS~CoV~2, the virus responsible for COVID~19. [provided by RefSeq, Apr 2020]