Rabbit Monoclonal Antibody to MAT1A

This gene catalyzes a two~step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S~adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S~adenosylmethionine is the source of methyl groups for most biological methylations. The encoded protein is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in this gene are associated with methionine adenosyltransferase deficiency. [provided by RefSeq, Jul 2008]