Rabbit Monoclonal Antibody to Alkyl~DHAP synthase

This gene is a member of the FAD~binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl~dihydroxyacetonephosphate (DHAP) is converted to alkyl~DHAP by the addition of a long chain alcohol and the removal of a long~chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]