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Rabbit Monoclonal Antibody to Cullin 1
Western blot detection of Cullin 1/CUL~1 in K562,C6 cell lysates using Cullin 1/CUL~1 antibody(1:1000 diluted).
Rabbit Monoclonal Antibody to Cullin 1

Rabbit Monoclonal Antibody to Cullin 1

  • 货号:

    57083
  • 别名:

    CUL1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,FCM
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13616
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to Cullin 1

Description

Core component of multiple cullin~RING~based SCF (SKP1~CUL1~F~box protein) E3 ubiquitin~protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. SCF complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins (PubMed:27565346). In the SCF complex, serves as a rigid scaffold that organizes the SKP1~F~box protein and RBX1 subunits.

Specification

Aliases CUL1
Swissprot Q13616
clone 9D1C7
WB Predicted band size 90kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen A synthesized peptide derived from it
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/1000
IF/ICC 1/20~1/50
FCM 1/20

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#57083