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Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and breast cancer (right) using RTN3 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human Liver tissues using RTN3 mouse mAb
HOT

Mouse Monoclonal Antibody to RTN3

  • 货号:

    20357
  • 别名:

    HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O95197
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to RTN3

Description

RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.

References

1. Biochem Biophys Res Commun. 2005 Sep 9;334(4):1198-205.
2. Brain Res Mol Brain Res. 2005 Aug 18;138(2):236-43.
3. FASEB J. 2003 Jul;17(10):1238-47.

Specification

Aliases HAP; ASYIP; NSPL2; NSPLII; RTN3-A1
Entrez GeneID 10313
Swissprot O95197
clone 10A8
WB Predicted band size 113kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of RTN3 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20357