Rabbit Monoclonal Antibody to ACADM

This gene encodes the medium~chain specific (C4 to C12 straight chain) acyl~Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta~oxidation pathway. Defects in this gene cause medium~chain acyl~CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]