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Rabbit Monoclonal Antibody to Cofilin
Western blot detection of Cofilin in A549,MCF~7,293T cell lysates using Cofilin antibody(1:1000 diluted).
Rabbit Monoclonal Antibody to Cofilin

Rabbit Monoclonal Antibody to Cofilin

  • 货号:

    56567
  • 别名:

    CFL; cofilin; HEL~S~15
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF,FCM
  • 反应种属:

    Human, Mouse, Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P23528
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to Cofilin

Description

The protein encoded by this gene can polymerize and depolymerize F~actin and G~actin in a pH~dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho~induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin~modulating protein that binds and depolymerizes filamentous F~actin and inhibits the polymerization of monomeric G~actin in a pH~dependent manner. It is involved in the translocation of actin~cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]

Specification

Aliases CFL; cofilin; HEL~S~15
Swissprot P23528
clone 6A2E3
WB Predicted band size 19kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen A synthesized peptide derived from it
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/1000
IHC 1/50
IF/ICC 1/50
FCM 1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#56567