Rabbit Monoclonal Antibody to MiTF

The protein encoded by this gene is a transcription factor that contains both basic helix~loop~helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell~specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory~pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]