Rabbit Monoclonal Antibody to NMDAR1

The protein encoded by this gene is a critical subunit of N~methyl~D~aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand~gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell~specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]