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Western blot detection of IRE1 (Phospho~Ser724) in K562 cell lysates using IRE1 (Phospho~Ser724) antibody(1:1000 diluted).
Rabbit Monoclonal Antibody to Phospho~IRE1 (Ser724)
-
货号：
56174 -
别名：
IRE1b; IRE2p; hIRE2p; IRE1~BETA -
应用：
WB -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
O75460 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to Phospho~IRE1 (Ser724)
Description |
|---|
Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N~terminal domain which leads to enzyme auto~activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C~terminus, converting it into a potent unfolded~protein response transcriptional activator and triggering growth arrest and apoptosis. |
Specification |
|
|---|---|
| Aliases | IRE1b; IRE2p; hIRE2p; IRE1~BETA |
| Swissprot | O75460 |
| clone | 3G6E2 |
| WB Predicted band size | 110kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from it |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000~1/5000 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#56174
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