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Western blot detection of Rb2 p130 (Phospho~Ser952) in K562,Hela cell lysates using Rb2 p130 (Phospho~Ser952) antibody(1:1000 diluted).
Rabbit Monoclonal Antibody to Phospho~Rb2 p130 (Ser952)
-
货号：
56160 -
别名：
Rb2; P130 -
应用：
WB,IHC,IF -
反应种属：
Human, Mouse -
抗体类型：
Primary antibody -
Swissprot：
Q08999 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to Phospho~Rb2 p130 (Ser952)
Description |
|---|
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys~20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin~modifying enzymes to promoters. |
Specification |
|
|---|---|
| Aliases | Rb2; P130 |
| Swissprot | Q08999 |
| clone | 8E2E8 |
| WB Predicted band size | 130kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | A synthesized peptide derived from it |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/2000~1/10000 |
| IHC | 1/20~1/100 |
| IF/ICC | 1/20~1/100 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#56160
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