Rabbit Monoclonal Antibody to Phospho~Chk1 (S280)

Description
Serine/threonine~protein kinase which is required for checkpoint~mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. May also negatively regulate cell cycle progression during unperturbed cell cycles.

Specification
Aliases	Checkpoint kinase 1; Chek1; Chk1; rad27;
Swissprot	O14757
clone	2E3B4
WB Predicted band size	54kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human Phospho~Chk1 (S280)
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000