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Rabbit Monoclonal Antibody to Osteoprotegerin
-
货号:
55871 -
别名:
OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1; -
应用:
IHC IF -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O00300 -
规格:
-
数量:
-+ -
说明书:
目录价¥1280
Rabbit Monoclonal Antibody to Osteoprotegerin
Description |
|---|
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis. |
Specification |
|
|---|---|
| Aliases | OCIF; OPG; Osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; TNFRSF11B; TR1; |
| Swissprot | O00300 |
| clone | 5B9G10 |
| WB Predicted band size | kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Osteoprotegerin |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#55871
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