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Rabbit Monoclonal Antibody to PAG
Western blot analysis of PAG expression in Raji cell lysate.
Rabbit Monoclonal Antibody to PAG

Rabbit Monoclonal Antibody to PAG

  • 货号:

    55809
  • 别名:

    CBP; Csk binding protein; PAG; PAG1;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IP FCM
  • 反应种属:

    Human Mouse Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9NWQ8
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to PAG

Description

Negatively regulates TCR (T~cell antigen receptor)~mediated signaling in T~cells and FCER1 (high affinity immunoglobulin epsilon receptor)~mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.

Specification

Aliases CBP; Csk binding protein; PAG; PAG1;
Swissprot Q9NWQ8
clone 6C9F6
WB Predicted band size 80kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human Mouse Rat
Immunogen A synthesized peptide derived from human PAG
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/500~1/2000
IP 1/50
IHC 1/50~1/200
FCM 1/100

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#55809