Rabbit Monoclonal Antibody to Smg1

Description
Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]~Q. Plays a central role in nonsense~mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1.

Specification
Aliases	61E3.4; ATX; hSMG1; LIP; smg1;
Swissprot	Q96Q15
clone	6H4H7
WB Predicted band size	410kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human Smg1
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000