Rabbit Monoclonal Antibody to SMCHD1

Description
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells.

Specification
Aliases	BAMS; FSHD2; Smchd1;
Swissprot	A6NHR9
clone	6E8E6
WB Predicted band size	226kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human
Immunogen	A synthesized peptide derived from human SMCHD1
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000
IHC	1/50~1/200