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Western blot analysis of Hamartin expression in HeLa cell lysate.
Rabbit Monoclonal Antibody to Hamartin
-
货号：
55607 -
别名：
Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1; -
应用：
WB IHC IF FCM -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q92574 -
规格：
-
数量：
-+ -
说明书：
目录价¥1280
Rabbit Monoclonal Antibody to Hamartin
Description |
|---|
In complex with TSC2, inhibits the nutrient~mediated or growth factor~stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule~mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
Specification |
|
|---|---|
| Aliases | Hamartin; kiaa0243; LAM; TSC; Tsc1; Tuberous sclerosis 1; |
| Swissprot | Q92574 |
| clone | 2E6F4 |
| WB Predicted band size | 150kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles. |
| Species Reactivity | Human |
| Immunogen | A synthesized peptide derived from human Hamartin |
| Formulation | 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
Application |
|
|---|---|
| WB | 1/1000~1/5000 |
| IHC | 1/50~1/200 |
| IF/ICC | 1/50~1/200 |
| FCM | 1/200 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#55607
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