Rabbit Monoclonal Antibody to Epac2

Description
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP~dependent, PKA~independent exocytosis through interaction with RIMS2.

Specification
Aliases	CAMP GEFII; CAMPGEFII; CGEF2; EPAC2; Rapgef4;
Swissprot	Q8WZA2
clone	7H6D4
WB Predicted band size	116kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human Epac2
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000