Rabbit Monoclonal Antibody to TrkB

Description
Receptor for brain~derived neurotrophic factor (BDNF), neurotrophin~3 and neurotrophin~4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine~protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI~3 kinase, and PLC~gamma~1.

Specification
Aliases	BDNF tropomyosine receptor kinase B; GP145 TrkB; GP145~TrkB/GP95~TrkB; GP95 TrkB; Neurotrophic receptor tyrosine kinase 2; Ntrk2; RATTRKB1; Tkrb; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B;
Swissprot	P15209(Mouse)
clone	8C5A9
WB Predicted band size	90,140kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Mouse Rat
Immunogen	A synthesized peptide derived from human TrkB
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000
IP	1/50
IHC	1/50~1/200