Rabbit Monoclonal Antibody to PIAS1

Description
Functions as an E3~type small ubiquitin~like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO~tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.

Specification
Aliases	DDXBP1; GBP; GU/RH~II; Pias1; ZMIZ3;
Swissprot	O75925
clone	2G2D2
WB Predicted band size	76kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human PIAS1
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/500~1/2000
IHC	1/50~1/200
IF/ICC	1/50~1/200
FCM	1/100