Rabbit Monoclonal Antibody to U1A

Description
Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre~mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri~snRNP. In a snRNP~free form (SF~A) may be involved in coupled pre~mRNA splicing and polyadenylation process.

Specification
Aliases	Mud1; snRNP A; SNRPA; U1~A; U1A;
Swissprot	P09012
clone	1B2F7
WB Predicted band size	31kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity	Human Mouse Rat
Immunogen	A synthesized peptide derived from human U1A
Formulation	1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application
WB	1/1000~1/5000
IP	1/50
IF/ICC	1/50~1/200