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Rabbit Monoclonal Antibody to SHC
Rabbit Monoclonal Antibody to SHC

Rabbit Monoclonal Antibody to SHC

  • 货号:

    55189
  • 别名:

    SH2 domain protein C1; SHC; SHC~transforming protein 1; SHCA; Src homology 2 domain~containing~transforming protein C1;
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB IHC IF FCM
  • 反应种属:

    Human Mouse Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P29353
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1280

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Rabbit Monoclonal Antibody to SHC

Description

Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.

Specification

Aliases SH2 domain protein C1; SHC; SHC~transforming protein 1; SHCA; Src homology 2 domain~containing~transforming protein C1;
Swissprot P29353
clone 6C10D6
WB Predicted band size 46,52,66kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at ~20°C long term. Avoid freeze~thaw cycles.
Species Reactivity Human Mouse Rat
Immunogen A synthesized peptide derived from human SHC
Formulation 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Application

WB 1/500~1/2000
IHC 1/50~1/200
IF/ICC 1/50~1/200
FCM 1/50

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#55189